1 - 5 Although single case reports discuss the clinical presentation of pneumonia caused by Escherichia coli or Actinobacillus spp., 6, 7 to the authors’ knowledge no large retrospective studies describe the … VCU Department of Radiology VCU Medical Center. K. pneumoniae is found in the normal flora of skin, mouth and intestines, where it does not cause disease. The spectrum includes. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases. Klebsiella pneumoniae- Pathogenicity and Clinical Manifestations. Hoffman NR, Preston FS. In nosocomial pneumonia, patchy bronchial pneumonia is the most common finding and is likely caused by Gram-negative pathogens, especially Pseudomonas or Klebsiella. Chronic Klebsiella pneumonia was diagnosed and ceftazidime was changed to ceftriaxone 1 g every 12 h for 2 weeks. Path. bulging of the horizontal fissure in this case) is less common nowadays with modern antibiotic treatment. the Western countries, Klebsiella pneumoniae invasive syn-drome (KPIS) should be alerted when patients present atypi-cal vague symptoms including fever, chill, nausea, vomiting, and right upper quadrant tenderness. Klebsiella pneumoniae renal abscess Zhonghua Yi Xue Za Zhi (Taipei). Figure Klebsiella pneumoniae liver abscess cases (n=123) in an outpatient parenteral antibiotic therapy (OPAT) cohort in Singapore, 2006–11 (n=2229) View Large Image Figure Viewer; Download Hi-res image Download (PPT) Roughly 70% of patients with K pneumoniae abscesses were men. Klebsiella pneumoniae(K. pneumoniae) is a Gram-negative, non-motile, capsulated, gas-producing enteric bacillus widely found in nature, and it belongs to the normal flora of the human oral cavity and intestine. Klebsiella species cause a wide range of diseases including pneumonia, urinary tract infections (UTIs), bloodstream infections and sepsis. … Often there can be extensive lobar opacification with air bronchograms. Complications of Klebsiella pneumonia: CT evaluation. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Klebsiella pneumonia, also known as Friedländer pneumonia, refers to pneumonia resulting from an infection from the organism Klebsiella pneumoniae. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Klebsiella pneumoniae was first described by a German microbiologist and pathologist Carl Friedländer in 1882. (2007) ISBN:B0011ZYZR2. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Necrotizing pneumonia can occur as a complication 6. Conversely, various pathogens give rise to identical radiologic findings; e.g., bronchopneumonia can be caused by, for example, Staphylococcus aureus, Klebsiella, Proteus, or Pseudomonas. {"url":"/signup-modal-props.json?lang=us\u0026email="}. Klebsiella is also responsible for a significant number of community-acquired infections. It is not possible radiologically to pinpoint the causative organism. However, in general, the type of microorganism implicated in pneumonia can be identified (bacteria, viruses, or fungi). On CXR, consolidation is lobar and resembles streptococcus pneumonia. Results: The mean age was 58.7 years and the male to female ratio was 10:14. This occurs early and progresses quickly. Often there can be extensive lobar opacification with air bronchograms. These bacteria are harmless when they’re in … The organism Klebsiella pneumoniae was first described by German microbiologist Carl Friedländer (1847-1887) in 1882, in a series of patients with Klebsiella pneumonia 7,8. by Wenlie Xie and Huixuan Jia. Unable to process the form. The Post-operative Abdomen - Surgicel … Klebsiella pneumoniae is a Gram-negative bacillus with worldwide distribution that usually causes respiratory and urinary tract infections, ... Four weeks after admission, following discussion with Radiology, a thoracic CT scan was performed for subsequent biopsy of one of the pulmonary lesions. After that, a 6-week course of amoxicillin-clavulanate (1 g every 12 h) was substituted. (1882) Virchow Arch. K pneumoniae monomicrobial liver abscesses were associated with diabetes mellitus (P <.001), higher blood glucose levels at admission (P <.05), predominantly solid US appearances (P <.001), irregular or indistinct lesion margins (P <.05), less than 2 mL of pus aspirated (P <.001), and longer duration of antibiotic treatment (P <.05). Check for errors and try again. J Comput Assist Tomogr. Microbiol. Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae: US Appearance and Aspiration Findings. [12,17] Aspiration pneumonia should always be suspected if the infiltrates are present bilaterally in the dependent or posterior portions of the lungs. K. pneumoniaewas first discovered by Friedlander in 1882 and considered to be responsible for a severe form of lobar pneumonia. Okada F, Ando Y, Honda K et-al. Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis. Friedlander's pneumonia. ADVERTISEMENT: Supporters see fewer/no ads. Radiology 2011. See additional information. Klebsiella pneumoniae, a gram-negative organism, is an emerging common cause of PLA, particularly in patients with poorly controlled diabetes mellitus and without any pre-existing liver disease. The three most common patterns are lobar pneumonia, bronchopneumonia, and interstitial pneumonia. Klebsiella pneumonia is a necrotizing process with a predilection for debilitated people. Massive necrosis (pulmonary gangrene) is a recognized complication. There can be variable features on chest HRCT which can also depend on current other organisms. It is an important type of pneumonia because of its severity, high incidence of complications, and elevated mortality [1]. Klebsiella spp. Imaging of Diseases of the Chest. It has a high mortality rate of approximately 50% even with antimicrobial therapy. Lobar expansion (e.g. Moon WK, Im JG, Yeon KM et-al. In the setting of pneumonia, infection with K. pneumoniae is confirmed by either sputum culture analysis, blood culture analysis or midstream urine depending upon the illness. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. This occurs early and progresses quickly. 2011;140 (4_MeetingAbstracts): . 2. 2010;83 (994): 854-60. Sputum analysis grew Klebsiella pneumoniae. The chest films of 58 patients with proved pneumonia due to Pseudomonas, Klebsiella, Enterobacter, Escherichia coli, Proteus, or Bacteroides were reviewed.Pseudomonas pneumonia was characterized by diffuse alveolar involvement with rapid progression to extensive macrocavitation. Mosby Incorporated. Friedlander, C. Über die Pseudomyceten bei der acuten fibrinösen Pneumoniae. Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium.It appears as a mucoid lactose fermenter on MacConkey agar.. CHEST Journal. Klebsiella pneumoniae is a bacterium that normally lives inside human intestines, where it doesn't cause disease.. The 70 isolates were taken from diverse clinical specimens. Unable to process the form. 01 Jul 2011 Radiology. K. pneumoniae is also a well-known cause of community-acquired pneumonia. There can b… 2008;21 (2): 305-33, table of contents. Radiology 2007. The disease is often overlooked in the Western physicians due to its rarity. Volume: 242 Issue: 3 pp. The past 3 decades have seen the emergence of an invasive liver abscess syndrome caused by Klebsiella pneumoniae that may manifest with metastatic infection to the eye, brain, or lung [1, 2]. All K. pneumoniae isolates were identified based on API 20 E and Vitek2 compact system. 5. All rights reserved. 27-05-2014 - Klebsiella pneumonia is refers to a pneumonia resulting from an infection from the organism Klebsiella pneumoniae. Also, lobar expansion is not specific for Klebsiella infection. To retrospectively compare the computed tomographic (CT) features of liver abscesses caused by Klebsiella pneumoniae with those caused by other bacterial pathogens. Authors S ... diagnostic radiology studies, therapeutic modalities and risk factors associated with mortality were studied. 7. E.Brant MW, A.Helms MC. This occurs early and progresses quickly. 3. ; Material is inoculated into blood agar and Mac Conkey agar medium and incubated aerobically. Rev. Klebsiella species are a Gram-negative rod shaped bacteria belonging to the Enterobacteriaceae family. {"url":"/signup-modal-props.json?lang=us\u0026email="}. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. Seventy of Klebsiella pneumoniae isolates had been collected from some Hospitals in Baghdad city from October to December 2017. Case of the Week: August 27-September 3, 2009. Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium that is found in the environment and has been associated with pneumonia in the alcoholic and diabetic patient population. Invasive community-acquired infections, including pyogenic liver abscesses, caused by hypervirulent Klebsiella pneumoniae (hvKp) strains have been well recognized worldwide. Volume: 260 Issue: 1 pp. Since 1950, 76 proved cases of pneumonia due to Staphylococcus aureus have been seen at the Los Angeles County Hospital. Klebsiella pneumoniae (K. pneumoniae) are bacteria that normally live in your intestines and feces. Anat. There has been a considerable increase in the incidence of this type of pneumonia beginning in 1954 and reaching a peak in 1956, with 21 cases. There tends to be a higher prevalence in older patients with alcoholism and debilitated hospitalized patients 3. On CXR, consolidation is lobar and resembles streptococcus pneumonia. are commonly implicated as a cause of bacterial pneumonia in horses, but few reports describe the clinical presentation and progression of disease attributable to this organism. Continuous improvement of the lesion was found on follow-up chest X-rays. 61-year-old woman with a long-standing history of alcohol abuse presented with a sudden onset of cough, pleuritic chest pain, dyspnea, fever, and rigors. Diagnosis: Klebsiella pneumonia (aka Friedländer’s pneumonia) - Images, diagnosis, treatment options, review - Thoracic Imaging Case. Less common forms of infection include cellular bronchiolitis, septic embolism, miliary infection, and lung abscess. Hansell DM. These infections are particularly a problem among neonates, elderly and immunocompromised individuals. Klebsiella pneumonia | Radiology Reference Article | Radiopaedia.org. Cavitary pulmonary disease. Check for errors and try again. The presence of gram-negative rods in Gram-stained smears suggests Klebsiella; they maybe capsulated and non-sporing. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Mosby Incorporated. Risk factors for Klebsiella pneumonia include alcoholism, diabetes mellitus, and COPD. Massive necrosis (pulmonary gangrene) is a recognized complication. CT Appearance of Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae. They are commonly found in the environment and in … ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Hansell DM. Gadkowski LB, Stout JE. The bacterium typically colonizes human mucosal … The hypervirulence of these novel community-acquired strains is mediated in part by their hypermucoviscous phenotypes associated with K1 and K2 capsule serotypes [ 3–5 ]. 6. (2009) ISBN:0723434964. 769-776. A report of 11 cases and appraisal of antibiotic therapy. Klebsiella pneumoniae is a Gram-negative bacteria and a well-known cause of community-acquired pneumonia, which accounts for less than 5% of all cases of pneumonia. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). Acute Klebsiella pneumoniae pneumonia alone and with concurrent infection: comparison of clinical and thin-section CT findings. Nineteen cases were seen in the first half of 1958. This organism can cause extensive pulmonary necrosis and frequent cavitation 1. © 2005 - 2021 WebMD LLC. Coronavirus: ... 2 Division of Diagnostic Radiology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. Klebsiella pneumonia usually results from aspiration of colonizing oropharyngeal microbes into the lower respiratory tract. Lippincott Williams &Wilkins. (1968) Diseases of the chest. 1. In comparison, cavitation is rare in pneumococcal pneumonia. 4. Recommended Articles. Chronic Klebsiella pneumonia: a rare manifestation of Klebsiella pneumonia. Ono A. Klebsiella pneumoniae is among the most common Gram-negative bacteria encountered by physicians worldwide and accounts for 0.5-5.0% of all cases of pneumonia 2. Introduction . 8. 1995;19 (2): 176-81. 87: 319. The Brant and Helms Solution. Pulmonary infection can also be classified into several radiologic and pathologic patterns according to its morphologic features. Extensive right upper lobe consolidation, with bulging of the horizontal fissure. Antibiotics sensitivity test was carried out toward 10 antibiotics using discs diffusion method. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. 53 (4): 481-6. Massive necrosis (pulmonary gangrene) is a recognized complication. Br J Radiol. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Imaging of Diseases of the Chest. (2009) ISBN:0723434964. Among these, sporadic hvKp-related community-acquired pneumonia (CAP) is an acute-onset, rapidly progressing disease that can likely turn fatal, if left untreated. Clin. 129-138. WebMD does not provide medical advice, diagnosis or treatment. 2000 Oct;63(10):721-8.

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